Anti-HRSV Pre-Fusion Glycoprotein Reference Antibody (RSM01, RUO) (VK421266)

Name: Anti-HRSV Pre-Fusion Glycoprotein Reference Antibody (RSM01, RUO)
Brand: abinScience
SKU: VK421266
Price: 176 USD
Availability: InStock

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Número de catálogo	VK421266
Reactividad de especies	Human respiratory syncytial virus A (HRSV-A)
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1
ID de clon	RSM01
Actividad biológica	RSM-01 tightly binds to the highly conserved Ø site on the Pre-F protein, blocks viral conformational changes, inhibits viral fusion with host cell membranes, and prevents viral entry into cells. It exhibits ultra-high neutralizing activity against both RSV subtype A and subtype B [1].
Objetivo	F, F1, F2, Fusion glycoprotein F0, Fusion glycoprotein F1, Fusion glycoprotein F2, Intervening segment, Pep27, Peptide 27, p27
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P03420, P11209, 12568, O36634, P13843
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	RSM-01, RSM01, RSM01
Fondo	Fusion glycoprotein F0 (Prefusion/Pre-F) is a ~63 kDa protein. Inactive precursor that is cleaved at two sites by a furin-like protease to give rise to the mature F1 and F2 fusion glycoproteins.
Referencias	1. Scotta MC, et al. Current strategies and perspectives for active and passive immunization against Respiratory Syncytial Virus in childhood. J Pediatr (Rio J). 2023;99 Suppl 1(Suppl 1):S4-S11. [VK421266]
Nota	For research use only. Not suitable for clinical or therapeutic use.