Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO) (HB949056)

Name: Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO)
Brand: abinScience
SKU: HB949056
Price: 370 USD
Availability: InStock

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Vista general

Número de catálogo	HB949056
Descripción	Anti-Human ACVR2A Antibody (Ab-14E1) (HB949056) is a research-grade recombinant antibody targeting ACVR2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Isotipo	IgG
ID de clon	Ab-14E1
Sistema de expresión	Mammalian cells
Objetivo	ACVR2, ACTRIIA, ACTR-IIA, Activin receptor type IIA, ACVR2A, Activin receptor type-2A
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P27037
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Activin receptor type-2A (ACVR2A) is a ~57 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6. 1. Renlund, N. et al. (2007) The Journal of endocrinology 195, 95-103. PMID: 17911401 2. Gray, PC. et al. (2000) The Journal of biological chemistry 275, 3206-12. PMID: 10652306
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human ACVR2A Antibody (Ab-14E1)

Referencias

Datasheet

Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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