Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO) (HB949056)

Name: Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO)
Brand: abinScience
SKU: HB949056
Price: 370 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB949056
Description	Anti-Human ACVR2A Antibody (Ab-14E1) (HB949056) is a research-grade recombinant antibody targeting ACVR2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Isotype	IgG
ID de clone	Ab-14E1
Système d'expression	Mammalian cells
Cible	ACVR2, ACTRIIA, ACTR-IIA, Activin receptor type IIA, ACVR2A, Activin receptor type-2A
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P27037
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Activin receptor type-2A (ACVR2A) is a ~57 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6. 1. Renlund, N. et al. (2007) The Journal of endocrinology 195, 95-103. PMID: 17911401 2. Gray, PC. et al. (2000) The Journal of biological chemistry 275, 3206-12. PMID: 10652306
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human ACVR2A Antibody (Ab-14E1)

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Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO).pdf

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