Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO) (HB949056)

Name: Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO)
Brand: abinScience
SKU: HB949056
Price: 370 USD
Availability: InStock

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概要

カタログ番号	HB949056
説明	Anti-Human ACVR2A Antibody (Ab-14E1) (HB949056) is a research-grade recombinant antibody targeting ACVR2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
アイソタイプ	IgG
クローンID	Ab-14E1
発現システム	Mammalian cells
ターゲット	ACVR2, ACTRIIA, ACTR-IIA, Activin receptor type IIA, ACVR2A, Activin receptor type-2A
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P27037
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Activin receptor type-2A (ACVR2A) is a ~57 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6. 1. Renlund, N. et al. (2007) The Journal of endocrinology 195, 95-103. PMID: 17911401 2. Gray, PC. et al. (2000) The Journal of biological chemistry 275, 3206-12. PMID: 10652306
注意事項	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human ACVR2A Antibody (Ab-14E1)

参考文献

データシート

Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO).pdf

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Anti-Human Activin RIIA Reference Antibody (Ab-14E1, RUO) (HB949056)

概要

イメージ

参考文献

データシート

SDS

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