Anti-Human Cyr61/CCN1 Reference Antibody (YM1B, RUO) (HT378016)

Name: Anti-Human Cyr61/CCN1 Reference Antibody (YM1B, RUO)
Brand: abinScience
SKU: HT378016
Price: 370 USD
Availability: InStock

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Numéro de catalogue	HT378016
Description	Anti-Human CCN1 (YM1B) (HT378016) is a research-grade recombinant antibody targeting Insulin-like growth factor-binding protein 10. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG
ID de clone	YM1B
Système d'expression	Mammalian cells
Nature	Recombinant
Cible	Insulin-like growth factor-binding protein 10, Protein GIG1, IGF-binding protein 10, CYR61, Cellular communication network factor 1, IBP-10, Cysteine-rich angiogenic inducer 61, GIG1, Protein CYR61, CCN1, IGFBP-10, IGFBP10, CCN family member 1
Niveau d'endotoxines	< 10 EU/mg as determined by LAL method.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	O00622
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	YM1B
Contexte	CCN family member 1 (CCN1/IGFBP10) is a ~42 kDa protein. Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CCN1-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human CCN1 (YM1B)

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Anti-Human Cyr61/CCN1 Reference Antibody (YM1B, RUO).pdf

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Anti-Human Cyr61/CCN1 Reference Antibody (YM1B, RUO) (HT378016)

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