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Anti-Human PVRIG Reference Antibody (GSK4381562, RUO) (HP700016)

Anti-Human PVRIG Reference Antibody (GSK4381562, RUO)
Anti-Human PVRIG Reference Antibody (GSK4381562, RUO)
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Aperçu
Numéro de catalogueHP700016
Description
Anti-Human CD112R/PVRIG (GSK4381562) (HP700016) is a research-grade recombinant antibody targeting CD112R. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1
ID de cloneGSK4381562
Système d'expression Mammalian cells
Cible C7orf15, CD112R, CD112 receptor receptor-related immunoglobulin domain-containing protein, PVRIG, Transmembrane protein PVRIG
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q6DKI7
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsanti-PVRIG, GSK-4381562, GSK'562, SRF813
Contexte

Transmembrane protein PVRIG (CD112R) is a ~34 kDa protein. Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human PVRIG Reference Antibody (GSK4381562, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CD112R/PVRIG (GSK4381562)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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