

| Número de catálogo | HB070086 |
|---|---|
| Descripción |
Research Grade Anti-Human CD120b/TNFRSF1B/TNFR2 (BI-1910) (HB070086) is a human monoclonal antibody. Suitable for Human.
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, FACS, Functional assay |
| Especie huésped | Human |
| Clonalidad | Monoclonal |
| Isotipo | IgG2, lambda |
| ID de clon | BI-1910 |
| Objetivo | TNF-R2, TNFR-II, p80 TNF-alpha receptor, Etanercept, TNFBR, TBP-2, TBPII, Tumor necrosis factor receptor superfamily member 1B, CD120b, p75, TNFRSF1B, Tumor necrosis factor receptor 2, TNF-RII, TNFR2, Tumor necrosis factor receptor type II |
| Nivel de endotoxinas | < 10 EU/mg |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P20333 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Fondo | Tumor necrosis factor receptor superfamily member 1B (CD120b/TNFR2) is a ~48 kDa protein. Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity. |
| Nota | For research use only. |
| Isotype Control | Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107) |




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