Anti-Human IL-2 R beta Reference Antibody (Mik beta 1, RUO) (HB912016)

Name: Anti-Human IL-2 R beta Reference Antibody (Mik beta 1, RUO)
Brand: abinScience
SKU: HB912016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB912016
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa
ID de clone	Mik beta 1
Système d'expression	Mammalian cells
Cible	IL-2R subunit beta, Interleukin-15 receptor subunit beta, IL2RB, IL-2 receptor subunit beta, CD122, High affinity IL-2 receptor subunit beta, p75, Interleukin-2 receptor subunit beta, IL-2RB, p70-75, IL15RB
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P14784
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Mik-beta-1, Mikbeta1, Mik-beta1
Contexte	Interleukin-2 receptor subunit beta (CD122/IL2RB) is a ~61 kDa protein. Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. 1. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770 2. Zhang, Z. et al. (2019) The Journal of experimental medicine 216, 1311-1327. PMID: 31040185
Reférences	1. J Hakimi, et al. Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC. J Immunol. 1993 Jul 15;151(2):1075-85. [HB912016]
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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Anti-Human IL-2 R beta Reference Antibody (Mik beta 1, RUO).pdf

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