

| Numéro de catalogue | HW342086 |
|---|---|
| Description |
Anti-Human OX40/TNFRSF4 Reference Antibody (INCAGN1949, RUO) (HW342086) is a human monoclonal antibody detecting OX40 Ligand/TNFSF4.
|
| Reactivité des espèces | Human |
| Applications | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Espèce hôte | Human |
| Clonalité | Monoclonal |
| Isotype | IgG |
| ID de clone | INCAGN1949 |
| Cible | ACT35 antigen, CD134, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, TNFRSF4, TXGP1L, Tumor necrosis factor receptor superfamily member 4 |
| Niveau d'endotoxines | < 10 EU/mg |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P43489 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | INCAGN1949 |
| Contexte | Tumor necrosis factor receptor superfamily member 4 (CD134/OX40) is a ~29 kDa protein. Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. |
| Reférences | 1. Gonzalez A M, et al. INCAGN1949, an anti-OX40 antibody with an optimal agonistic profile and the ability to selectively deplete intratumoral regulatory T cells[J]. Cancer Research, 2017, 77(13_Supplement): 4703-4703. [HW342086] |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anti-Human CD134/TNFRSF4/OX40 (INCAGN1949)




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