Anti-Human CD155/PVR Reference Antibody (Ntx1088, RUO) (HB135026)

Name: Anti-Human CD155/PVR Reference Antibody (Ntx1088, RUO)
Brand: abinScience
SKU: HB135026
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB135026
Description	Anti-Human CD155/PVR Antibody (Ntx1088) (HB135026) is a research-grade recombinant antibody targeting CD155. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Isotype	IgG4-kappa
ID de clone	Ntx1088
Système d'expression	Mammalian cells
Cible	Nectin-like protein 5 receptor, CD155, PVR, PVS, NECL-5
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P15151
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Ntx1088, Ntx1088, Ntx-1088
Contexte	Poliovirus receptor (CD155/PVR) is a ~45 kDa protein. Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD155/PVR Antibody (Ntx1088)
Bioactivity

Detects recombinant human CD155/PVR (Catalog No: HB135011) in indirect ELISA
Flow cytometry

Flow-cytometry using anti-human CD155 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD155 monoclonal antibody (Catalog HB135026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.