Anti-Human CD155/PVR Reference Antibody (Ntx1088, RUO) (HB135026)

Name: Anti-Human CD155/PVR Reference Antibody (Ntx1088, RUO)
Brand: abinScience
SKU: HB135026
Price: 176 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HB135026
説明	Anti-Human CD155/PVR Antibody (Ntx1088) (HB135026) is a research-grade recombinant antibody targeting CD155. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
アイソタイプ	IgG4-kappa
クローンID	Ntx1088
発現システム	Mammalian cells
ターゲット	Nectin-like protein 5 receptor, CD155, PVR, PVS, NECL-5
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P15151
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	Ntx1088, Ntx1088, Ntx-1088
背景	Poliovirus receptor (CD155/PVR) is a ~45 kDa protein. Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell.
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

イメージ

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD155/PVR Antibody (Ntx1088)
Bioactivity

Detects recombinant human CD155/PVR (Catalog No: HB135011) in indirect ELISA
Flow cytometry

Flow-cytometry using anti-human CD155 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD155 monoclonal antibody (Catalog HB135026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.