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| カタログ番号 | HX902016 |
|---|---|
| 説明 |
Anti-Human CD202b/TEK/TIE-2 (UBX2050) (HX902016) is a research-grade recombinant antibody targeting CD202. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | UBX2050 |
| 発現システム | Mammalian cells |
| ターゲット | VMCM, TIE2, Tunica interna endothelial cell kinase, CD202b, Tyrosine-protein kinase receptor TIE-2, TEK, Angiopoietin-1 receptor, VMCM1, Endothelial tyrosine kinase, Tyrosine-protein kinase receptor TEK, p140 TEK, Tyrosine kinase with Ig and EGF homology domains-2, hTIE2 |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q02763 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | UBX2050 |
| 背景 | Angiopoietin-1 receptor (CD202b/TEK) is a ~125 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of pro-inflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angiogenesis, depending on the context. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human CD202b/TEK/TIE-2 (UBX2050)
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