Anti-Human TLR3 Reference Antibody (CNTO5429, RUO) (HT477026)

Name: Anti-Human TLR3 Reference Antibody (CNTO5429, RUO)
Brand: abinScience
SKU: HT477026
Price: 326 USD
Availability: InStock

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Número de catálogo	HT477026
Descripción	Anti-Human CD283/TLR3 (CNTO5429) (HT477026) is a research-grade recombinant antibody targeting CD283. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	CNTO5429
Sistema de expresión	Mammalian cells
Objetivo	TLR3, CD283, Toll-like receptor 3
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	O15455
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CNTO5429
Fondo	Toll-like receptor 3 (CD283/TLR3) is a ~103 kDa protein. Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Nota	For research use only. Not suitable for clinical or therapeutic use.