Anti-Human TLR3 Reference Antibody (CNTO5429, RUO) (HT477026)

Name: Anti-Human TLR3 Reference Antibody (CNTO5429, RUO)
Brand: abinScience
SKU: HT477026
Price: 326 USD
Availability: InStock

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概要
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概要

カタログ番号	HT477026
説明	Anti-Human CD283/TLR3 (CNTO5429) (HT477026) is a research-grade recombinant antibody targeting CD283. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG
クローンID	CNTO5429
発現システム	Mammalian cells
ターゲット	TLR3, CD283, Toll-like receptor 3
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	O15455
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	CNTO5429
背景	Toll-like receptor 3 (CD283/TLR3) is a ~103 kDa protein. Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
注意事項	For research use only. Not suitable for clinical or therapeutic use.