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Anti-Human CD46 Reference Antibody (FOR46, RUO) (HB735016)

Anti-Human CD46 Reference Antibody (FOR46, RUO)
Anti-Human CD46 Reference Antibody (FOR46, RUO)
Anti-Human CD46 Reference Antibody (FOR46, RUO)
Anti-Human CD46 Reference Antibody (FOR46, RUO)
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Especificación:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
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Vista general
Número de catálogoHB735016
Descripción
Anti-Human CD46 Antibody (FOR46) (HB735016) is a research-grade recombinant antibody targeting CD46. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huéspedHuman
IsotipoIgG
ID de clonFOR46
Sistema de expresión Mammalian cells
Objetivo Trophoblast leukocyte common antigen, CD46, TLX, MCP, Membrane cofactor protein, MIC10
Nivel de endotoxinas < 10 EU/mg
Pureza >95% purity as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P15529
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosFOR46, FOR46, FOR-46
Fondo

Membrane cofactor protein (CD46) is a ~43 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.

Nota For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107)
Imágenes
  • Anti-Human CD46 Reference Antibody (FOR46, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CD46 Antibody (FOR46)

  • Anti-Human CD46 Reference Antibody (FOR46, RUO)

    Bioactivity

    Detects recombinant CD46 (Catalog No: HB735011) in indirect ELISA.

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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