Anti-Human CD46 Reference Antibody (FOR46, RUO) (HB735016)

Name: Anti-Human CD46 Reference Antibody (FOR46, RUO)
Brand: abinScience
SKU: HB735016
Price: 370 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB735016
Description	Anti-Human CD46 Antibody (FOR46) (HB735016) is a research-grade recombinant antibody targeting CD46. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Isotype	IgG
ID de clone	FOR46
Système d'expression	Mammalian cells
Cible	Trophoblast leukocyte common antigen, CD46, TLX, MCP, Membrane cofactor protein, MIC10
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P15529
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	FOR46, FOR46, FOR-46
Contexte	Membrane cofactor protein (CD46) is a ~43 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107)

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD46 Antibody (FOR46)
Bioactivity

Detects recombinant CD46 (Catalog No: HB735011) in indirect ELISA.

Reférences

Fiche technique

Anti-Human CD46 Reference Antibody (FOR46, RUO).pdf

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Formula

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