Anti-Human CD46 Reference Antibody (FOR46, RUO) (HB735016)

Name: Anti-Human CD46 Reference Antibody (FOR46, RUO)
Brand: abinScience
SKU: HB735016
Price: 370 USD
Availability: InStock

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Обзор

Каталожный номер	HB735016
Описание	Anti-Human CD46 Antibody (FOR46) (HB735016) is a research-grade recombinant antibody targeting CD46. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Изотип	IgG
ID клона	FOR46
Система экспрессии	Mammalian cells
Цель	Trophoblast leukocyte common antigen, CD46, TLX, MCP, Membrane cofactor protein, MIC10
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P15529
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	FOR46, FOR46, FOR-46
Фон	Membrane cofactor protein (CD46) is a ~43 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107)

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD46 Antibody (FOR46)
Bioactivity

Detects recombinant CD46 (Catalog No: HB735011) in indirect ELISA.

Ссылки

Даташит

Anti-Human CD46 Reference Antibody (FOR46, RUO).pdf

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Formula

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