Anti-Human Transferrin R/TfR Reference Antibody (CX-2029, RUO) (HY036056)

Name: Anti-Human Transferrin R/TfR Reference Antibody (CX-2029, RUO)
Brand: abinScience
SKU: HY036056
Price: 326 USD
Availability: InStock

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Спецификация:

100ug
1mg
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Обзор

Каталожный номер

HY036056

Описание

Anti-Human CD71/TFRC (CX-2029) (HY036056) is a research-grade recombinant antibody targeting CD71. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Реактивность видов

Human

Применения

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

Хозяинский вид

Human

Клоональность

Monoclonal

Изотип

IgG

ID клона

CX-2029

Система экспрессии

Mammalian cells

Характер

Recombinant

Цель

CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor 1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR

Уровень эндотоксинов

< 10 EU/mg as determined by LAL method.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P02786

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Альтернативные названия

CX-2029, CX2029, CX2029

Фон

Transferrin receptor protein 1 (CD71/TFRC) is a ~84 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

1. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738

2. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240

Примечание

For research use only. Not suitable for clinical or therapeutic use.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human Transferrin R/TfR Reference Antibody (CX-2029, RUO)

Ссылки

Даташит

Anti-Human Transferrin R/TfR Reference Antibody (CX-2029, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human Transferrin R/TfR Reference Antibody (CX-2029, RUO) (HY036056)

Обзор

Изображения

Ссылки

Даташит

SDS