Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (IBI-325, RUO) (HB209186)

Name: Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (IBI-325, RUO)
Brand: abinScience
SKU: HB209186
Price: 370 USD
Availability: InStock

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Especificación:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

Número:

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Vista general
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Referencias
Datasheet
SDS

Vista general

Número de catálogo

HB209186

Descripción

Anti-Human CD73/NT5E (IBI-325) (HB209186) is a research-grade recombinant antibody targeting CD73.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.

Reactividad de especies

Human

Aplicaciones

ELISA, FCM, Functional assay

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

IgG4, kappa (F234A, L234A)

ID de clon

IBI-325

Objetivo

5'-NT, 5'-deoxynucleotidase, 5'-nucleotidase, CD73, EC:3.1.3.35, EC:3.1.3.5, EC:3.1.3.89, EC:3.1.3.91, EC:3.1.3.99, Ecto-5'-nucleotidase, IMP-specific 5'-nucleotidase, NT5, NT5E, NTE, Thymidylate 5'-phosphatase

Nivel de endotoxinas

< 10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P21589

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

5'-nucleotidase (CD73/NT5E) is a ~63 kDa protein. Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN.

1. Garavaglia, S. et al. (2012) The Biochemical journal 441, 131-41. PMID: 21933152

2. Heuts, DP. et al. (2012) Chembiochem : a European journal of chemical biology 13, 2384-91. PMID: 22997138

3. Knapp, K. et al. (2012) Structure (London, England : 1993) 20, 2161-73. PMID: 23142347

4. Fausther, M. et al. (2014) PloS one 9, e98568. PMID: 24887587

5. Scaletti, E. et al. (2021) Purinergic signalling 17, 693-704. PMID: 34403084

Nota

For research use only.

Imágenes