Anti-Human ST6GAL1/CD75 Reference Antibody (EBU-141 Tetra, RUO) (HB145016)

Name: Anti-Human ST6GAL1/CD75 Reference Antibody (EBU-141 Tetra, RUO)
Brand: abinScience
SKU: HB145016
Price: 326 USD
Availability: InStock

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Número de catálogo	HB145016
Descripción	Anti-Human CD75/ST6GAL1 (EBU-141 Tetra) (HB145016) is a research-grade recombinant antibody targeting CD75. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	EBU-141 Tetra
Sistema de expresión	Mammalian cells
Objetivo	Alpha 2, 6-ST 1, B-cell antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 6-sialyltransferase 1, SIAT1, Sialyltransferase 1, ST6GAL1, ST6Gal I, Beta-galactoside alpha-2, 6-sialyltransferase 1, ST6GalI
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P15907
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	EBU-141Tetra, EBU141Tetra, EBU141Tetra
Fondo	Beta-galactoside alpha-2,6-sialyltransferase 1 (CD75/ST6GAL1) is a ~46 kDa protein. Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. In B lymphocytes, generates neuraminidase-sensitive lymphocyte cell-surface differentiation antigens, such as CDw75, HB-6 and CD76. Sialylates complex-type N-glycans attached on the fragment crystallizable (Fc) of IgGs confering anti-inflammatory effector functions. Preferentially monosialylates the alpha(1->3) mannose antenna of Fc glycoforms with subsequent disialylation occurring at a much slower rate. 1. Bast, BJ. et al. (1992) The Journal of cell biology 116, 423-35. PMID: 1730763
Nota	For research use only. Not suitable for clinical or therapeutic use.