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Anti-Human OCIL/CLEC2D Reference Antibody (ZM008, RUO) (HP960016)

Anti-Human OCIL/CLEC2D Reference Antibody (ZM008, RUO)
Anti-Human OCIL/CLEC2D Reference Antibody (ZM008, RUO)
Anti-Human OCIL/CLEC2D Reference Antibody (ZM008, RUO)
Anti-Human OCIL/CLEC2D Reference Antibody (ZM008, RUO)
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Aperçu
Numéro de catalogueHP960016
Description
Anti-Human CLEC2D/OCIL/LLT1 (ZM008) (HP960016) is a research-grade recombinant antibody targeting CLAX. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG
ID de cloneZM008
Système d'expression Mammalian cells
Cible CLAX, C-type lectin domain family 2 member D, Osteoclast inhibitory lectin, CLEC2D, Lectin-like transcript 1, Lectin-like NK cell receptor, OCIL, LLT-1, LLT1
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q9UHP7
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsZM008
Contexte

C-type lectin domain family 2 member D (CLEC2D/OCIL) is a ~21 kDa protein. Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.

1. Rosen, DB. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7796-9. PMID: 16339513
2. Germain, C. et al. (2010) The Journal of biological chemistry 285, 36207-15. PMID: 20843815
3. Hu, YS. et al. (2004) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19, 89-99. PMID: 14753741
4. Gange, CT. et al. (2004) The Journal of biological chemistry 279, 29043-9. PMID: 15123656
5. Mathew, PA. et al. (2004) Molecular immunology 40, 1157-63. PMID: 15104121
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Images
  • Anti-Human OCIL/CLEC2D Reference Antibody (ZM008, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CLEC2D/OCIL/LLT1 (ZM008)

  • Anti-Human OCIL/CLEC2D Reference Antibody (ZM008, RUO)

    Bioactivity

    Detects recombinant human CLEC2D/OCIL/LLT1 (Catalog No: HP960012) in indirect ELISA

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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