中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HY106026 |
|---|---|
| 説明 |
Anti-Human Complement C2 Antibody (ARGX-117) (HY106026) is a research-grade recombinant antibody targeting Complement C2. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | ARGX-117 |
| 発現システム | Mammalian cells |
| 性質 | Recombinant |
| ターゲット | Complement C2, C2, C3/C5 convertase |
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P06681 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | ARGX-117, ARGX117, ARGX117 |
| 背景 | Complement C2 is a ~83 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Component C2 is part of the classical, lectin and GZMK complement systems. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Milder, FJ. et al. (2006) Structure (London, England : 1993) 14, 1587-97. PMID: 17027507 3. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 4. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 5. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882 6. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human Complement C2 Antibody (ARGX-117)
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
