Anti-Human M-CSF Reference Antibody (PD-0360324, RUO) (HY515036)

Name: Anti-Human M-CSF Reference Antibody (PD-0360324, RUO)
Brand: abinScience
SKU: HY515036
Price: 370 USD
Availability: InStock

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100ug
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Referencias
Datasheet
SDS

Vista general

Número de catálogo	HY515036
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	PD-0360324
Actividad biológica	CSF1 serves as a fluorescent sensor for the specific recognition of Cu + in aqueous buffer systems, with a K d value of 0.49 pM, and its fluorescence response increases 17-fold upon binding to Cu + [1].
Sistema de expresión	Mammalian cells
Objetivo	CSF1, Macrophage colony-stimulating factor 1, CSF-1, Lanimostim, M-CSF, MCSF
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P09603
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	PD-0360324, PD0360324, PD0360324
Fondo	Macrophage colony-stimulating factor 1 (CSF1/M-CSF) is a ~60 kDa protein. Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.
Referencias	1. Jia S, et al. Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores. ACS Chem Biol. 2018;13(7):1844-1852. [HY515036]
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)

Imágenes

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CSF1/M-CSF (PD-0360324)
Bioactivity

Detects recombinant human CSF1/M-CSF (Catalog No: HY515011) in indirect ELISA