Anti-Human M-CSF Reference Antibody (PD-0360324, RUO) (HY515036)

Name: Anti-Human M-CSF Reference Antibody (PD-0360324, RUO)
Brand: abinScience
SKU: HY515036
Price: 370 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue	HY515036
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG
ID de clone	PD-0360324
Activité biologique	CSF1 serves as a fluorescent sensor for the specific recognition of Cu + in aqueous buffer systems, with a K d value of 0.49 pM, and its fluorescence response increases 17-fold upon binding to Cu + [1].
Système d'expression	Mammalian cells
Cible	CSF1, Macrophage colony-stimulating factor 1, CSF-1, Lanimostim, M-CSF, MCSF
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P09603
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	PD-0360324, PD0360324, PD0360324
Contexte	Macrophage colony-stimulating factor 1 (CSF1/M-CSF) is a ~60 kDa protein. Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.
Reférences	1. Jia S, et al. Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores. ACS Chem Biol. 2018;13(7):1844-1852. [HY515036]
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)

Images

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CSF1/M-CSF (PD-0360324)
Bioactivity

Detects recombinant human CSF1/M-CSF (Catalog No: HY515011) in indirect ELISA