Anti-Human M-CSF Reference Antibody (PD-0360324, RUO) (HY515036)

Name: Anti-Human M-CSF Reference Antibody (PD-0360324, RUO)
Brand: abinScience
SKU: HY515036
Price: 370 USD
Availability: InStock

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100ug
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Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер	HY515036
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG
ID клона	PD-0360324
Биологическая активность	CSF1 serves as a fluorescent sensor for the specific recognition of Cu + in aqueous buffer systems, with a K d value of 0.49 pM, and its fluorescence response increases 17-fold upon binding to Cu + [1].
Система экспрессии	Mammalian cells
Цель	CSF1, Macrophage colony-stimulating factor 1, CSF-1, Lanimostim, M-CSF, MCSF
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P09603
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	PD-0360324, PD0360324, PD0360324
Фон	Macrophage colony-stimulating factor 1 (CSF1/M-CSF) is a ~60 kDa protein. Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.
Ссылки	1. Jia S, et al. Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores. ACS Chem Biol. 2018;13(7):1844-1852. [HY515036]
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CSF1/M-CSF (PD-0360324)
Bioactivity

Detects recombinant human CSF1/M-CSF (Catalog No: HY515011) in indirect ELISA