Anti-Human DLL3 Reference Antibody (AMG 119, RUO) (HP628036)

Name: Anti-Human DLL3 Reference Antibody (AMG 119, RUO)
Brand: abinScience
SKU: HP628036
Price: 370 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HP628036
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG
ID de clone	AMG 119
Système d'expression	Mammalian cells
Cible	Drosophila Delta homolog 3, Delta3, Delta-like protein 3, DLL3
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q9NYJ7
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	AMG-119, AMG119, AMG119
Contexte	Delta-like protein 3 (DLL3) is a ~64 kDa protein. Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
Reférences	1. Zhou D, et al. Clinical Pharmacology Profile of AMG 119, the First Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting Delta-Like Ligand 3 (DLL3), in Patients with Relapsed/Refractory Small Cell Lung Cancer (SCLC). J Clin Pharmacol. 2024 Mar;64(3):362-370. [HP628036]
Note	For research use only. Not suitable for clinical or therapeutic use.