Anti-Human EDNRB/Endothelin R Type B Reference Antibody (DEDN6526A, RUO) (HB173016)

Name: Anti-Human EDNRB/Endothelin R Type B Reference Antibody (DEDN6526A, RUO)
Brand: abinScience
SKU: HB173016
Price: 370 USD
Availability: InStock

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Numéro de catalogue	HB173016
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Isotype	IgG
ID de clone	DEDN6526A
Système d'expression	Mammalian cells
Cible	Endothelin receptor type B, EDNRB, ETRB, ET-BR, Endothelin receptor non-selective type, ET-B
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P24530
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	DEDN6526A, DEDN6526A, DEDN-6526A
Contexte	Endothelin receptor type B (EDNRB/ETRB) is a ~49 kDa protein. Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Reférences	1. Sandhu S, et al. Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma. Invest New Drugs. 2020 Jun;38(3):844-854. [HB173016]
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human EDNRB/ETRB Antibody (DEDN6526A)

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Anti-Human EDNRB/Endothelin R Type B Reference Antibody (DEDN6526A, RUO).pdf

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