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| カタログ番号 | HF987016 |
|---|---|
| 説明 |
Anti-Human Factor VIII Reference Antibody (TB-402, RUO) (HF987016) is a human monoclonal antibody detecting Factor VIII. Expressed in Mammalian cells.
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | TB-402 |
| 発現システム | Mammalian cells |
| 性質 | Recombinant |
| ターゲット | AHF, Procoagulant component, Coagulation factor VIII, Antihemophilic factor, F8C, F8 |
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P00451 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | TB-402, TB402, TB402 |
| 背景 | Coagulation factor VIII (F8) is a ~267 kDa protein. Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa. |
| 参考文献 | 1. Verhamme P, et al. Single intravenous administration of TB-402 for the prophylaxis of venous thromboembolism after total knee replacement: a dose-escalating, randomized, controlled trial. J Thromb Haemost. 2011 Apr;9(4):664-71. [HF987016] |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) |
SDS-PAGE for Research Grade Anti-Human F8 (TB-402)
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