Anti-Human IL-11R alpha Reference Antibody (LASN 01, RUO) (HC604036)

Name: Anti-Human IL-11R alpha Reference Antibody (LASN 01, RUO)
Brand: abinScience
SKU: HC604036
Price: 176 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HC604036
説明	Anti-Human IL11RA Antibody (LASN 01) (HC604036) is a research-grade recombinant antibody targeting IL-11RA. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
アイソタイプ	IgG1
クローンID	LASN 01
発現システム	Mammalian cells
テスト済みアプリケーション	FCM
ターゲット	IL-11RA, sIL-11R, Interleukin-11 receptor subunit alpha, sIL-11RA, IL11RA, IL-11R-alpha, IL-11R subunit alpha, IL-11 receptor subunit alpha, sIL11RA
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q14626
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	LASN01, LASN-01, LASN01
背景	Interleukin-11 receptor subunit alpha (IL11RA) is a ~45 kDa protein. Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

イメージ

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human IL11RA Antibody (LASN 01)
Flow cytometry

Flow-cytometry using anti-human IL11RA antibody. Hela cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human IL11RA monoclonal antibody (Catalog HC604036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.