Anti-Human IL-11R alpha Reference Antibody (X209, RUO) (HC604016)

Name: Anti-Human IL-11R alpha Reference Antibody (X209, RUO)
Brand: abinScience
SKU: HC604016
Price: 176 USD
Availability: InStock

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Reférences
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SDS

Aperçu

Numéro de catalogue

HC604016

Description

Anti-Human IL11RA Antibody (X209) (HC604016) is a research-grade recombinant antibody targeting IL-11RA. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Reactivité des espèces

Human

Applications

ELISA, WB, Bioactivity: FACS, Functional assay, Research in vivo

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG4, kappa

ID de clone

X209

Système d'expression

Mammalian cells

Applications testées

Cible

IL-11RA, sIL-11R, Interleukin-11 receptor subunit alpha, sIL-11RA, IL11RA, IL-11R-alpha, IL-11R subunit alpha, IL-11 receptor subunit alpha, sIL11RA

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q14626

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Noms alternatifs

EnX209

Contexte

Interleukin-11 receptor subunit alpha (IL11RA) is a ~45 kDa protein. Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107)
Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

Images

Bioactivity

Detects Recombinant Human IL11RA Protein, C-His (Cat No.: HC604011) in indirect ELISA.
SDS-PAGE

SDS-PAGE for Research Grade Anti-Human IL11RA Antibody (X209).
Western blot

Western blot analysis was performed using anti-IL11RA monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human IL11RA (Catalog No: HC604011)