Anti-Human IL-21 Reference Antibody (NNC-114-0005, RUO) (HV658026)

Name: Anti-Human IL-21 Reference Antibody (NNC-114-0005, RUO)
Brand: abinScience
SKU: HV658026
Price: 176 USD
Availability: InStock

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Vista general

Número de catálogo	HV658026
Descripción	Anti-Human IL21 (NNC-114-0005) (HV658026) is a research-grade recombinant antibody targeting IL-21. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa
ID de clon	NNC-114-0005
Sistema de expresión	Mammalian cells
Aplicaciones probadas	WB
Objetivo	IL-21, Interleukin-21, IL21, Za11
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q9HBE4
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	NNC-114-0005, NNC-114-0005
Fondo	Interleukin-21 (IL21) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. 1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504 2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human IL21 (NNC-114-0005).
Western blot

Western blot analysis was performed using anti-IL21 monoclonal antibody at 1µg/ml on various samples.
Lane 1: recombinant human IL21 (Catalog No: HV658012)
Lane 2: negative control