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| カタログ番号 | HV658026 |
|---|---|
| 説明 |
Anti-Human IL21 (NNC-114-0005) (HV658026) is a research-grade recombinant antibody targeting IL-21. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1-kappa |
| クローンID | NNC-114-0005 |
| 発現システム | Mammalian cells |
| テスト済みアプリケーション | WB |
| ターゲット | IL-21, Interleukin-21, IL21, Za11 |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q9HBE4 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | NNC-114-0005, NNC-114-0005 |
| 背景 | Interleukin-21 (IL21) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. 1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504 2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human IL21 (NNC-114-0005).
Western blot analysis was performed using anti-IL21 monoclonal antibody at 1µg/ml on various samples.
Lane 1: recombinant human IL21 (Catalog No: HV658012)
Lane 2: negative control
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