



| Каталожный номер | HV658026 |
|---|---|
| Описание |
Anti-Human IL21 (NNC-114-0005) (HV658026) is a research-grade recombinant antibody targeting IL-21. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Реактивность видов | Human |
| Применения | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG1-kappa |
| ID клона | NNC-114-0005 |
| Система экспрессии | Mammalian cells |
| Проверенные приложения | WB |
| Цель | IL-21, Interleukin-21, IL21, Za11 |
| Уровень эндотоксинов | < 10 EU/mg |
| Чистота | >95% purity as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q9HBE4 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | NNC-114-0005, NNC-114-0005 |
| Фон | Interleukin-21 (IL21) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. 1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504 2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704 |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anti-Human IL21 (NNC-114-0005).

Western blot analysis was performed using anti-IL21 monoclonal antibody at 1µg/ml on various samples.
Lane 1: recombinant human IL21 (Catalog No: HV658012)
Lane 2: negative control




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