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Anti-Human IL-21 Reference Antibody (NNC-114-0005, RUO) (HV658026)

Anti-Human IL-21 Reference Antibody (NNC-114-0005, RUO)
Anti-Human IL-21 Reference Antibody (NNC-114-0005, RUO)
Anti-Human IL-21 Reference Antibody (NNC-114-0005, RUO)
Anti-Human IL-21 Reference Antibody (NNC-114-0005, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHV658026
Описание
Anti-Human IL21 (NNC-114-0005) (HV658026) is a research-grade recombinant antibody targeting IL-21. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1-kappa
ID клонаNNC-114-0005
Система экспрессии Mammalian cells
Проверенные приложения WB
Цель IL-21, Interleukin-21, IL21, Za11
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q9HBE4
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияNNC-114-0005, NNC-114-0005
Фон

Interleukin-21 (IL21) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection.

1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504
2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Anti-Human IL-21 Reference Antibody (NNC-114-0005, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human IL21 (NNC-114-0005).

  • Anti-Human IL-21 Reference Antibody (NNC-114-0005, RUO)

    Western blot

    Western blot analysis was performed using anti-IL21 monoclonal antibody at 1µg/ml on various samples.
    Lane 1: recombinant human IL21 (Catalog No: HV658012)
    Lane 2: negative control

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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