Anti-Human IL-22 R alpha 1 Reference Antibody (ARGX-112, RUO) (HV951046)

Name: Anti-Human IL-22 R alpha 1 Reference Antibody (ARGX-112, RUO)
Brand: abinScience
SKU: HV951046
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HV951046
Description	Anti-Human IL22RA1 Antibody (ARGX-112) (HV951046) is a research-grade recombinant antibody targeting CRF2-9. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1
ID de clone	ARGX-112
Système d'expression	Mammalian cells
Cible	CRF2-9, IL-22RA1, IL22RA1, ZcytoR11, IL-22R-alpha-1, IL-22 receptor subunit alpha-1, Cytokine receptor class-II member 9, Interleukin-22 receptor subunit alpha-1, Cytokine receptor family 2 member 9, IL22R
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q8N6P7
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ARGX-112, ARGX112, ARGX112
Contexte	Interleukin-22 receptor subunit alpha-1 (IL22RA1/IL22R) is a ~63 kDa protein. Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107)