中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HW363016 |
|---|---|
| 説明 |
Anti-Human NAMPT Antibody (Alt-100) (HW363016) is a research-grade recombinant antibody targeting NAMPT. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| アイソタイプ | IgG |
| クローンID | Alt-100 |
| 発現システム | Mammalian cells |
| ターゲット | NAMPT, Pre-B-cell colony-enhancing factor 1, NAmPRTase, Pre-B cell-enhancing factor, Nicotinamide phosphoribosyltransferase, Visfatin, PBEF, PBEF1, Nampt |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P43490 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | Alt-100, Alt100, Alt100 |
| 背景 | Nicotinamide phosphoribosyltransferase (NAMPT) is a ~55 kDa protein. Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human NAMPT Antibody (Alt-100)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
