Anti-Human PBEF/Visfatin Reference Antibody (Alt-100, RUO) (HW363016)

Name: Anti-Human PBEF/Visfatin Reference Antibody (Alt-100, RUO)
Brand: abinScience
SKU: HW363016
Price: 370 USD
Availability: InStock

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100ug
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Обзор

Каталожный номер	HW363016
Описание	Anti-Human NAMPT Antibody (Alt-100) (HW363016) is a research-grade recombinant antibody targeting NAMPT. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Изотип	IgG
ID клона	Alt-100
Система экспрессии	Mammalian cells
Цель	NAMPT, Pre-B-cell colony-enhancing factor 1, NAmPRTase, Pre-B cell-enhancing factor, Nicotinamide phosphoribosyltransferase, Visfatin, PBEF, PBEF1, Nampt
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P43490
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Alt-100, Alt100, Alt100
Фон	Nicotinamide phosphoribosyltransferase (NAMPT) is a ~55 kDa protein. Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human NAMPT Antibody (Alt-100)

Ссылки

Даташит

Anti-Human PBEF/Visfatin Reference Antibody (Alt-100, RUO).pdf

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