中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HV701016 |
|---|---|
| 説明 |
Anti-Human NOTCH3 (PF-06650808) (HV701016) is a research-grade recombinant antibody targeting Neurogenic locus notch homolog protein 3. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | PF-06650808 |
| 発現システム | Mammalian cells |
| ターゲット | Neurogenic locus notch homolog protein 3, NOTCH3, Notch 3 |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q9UM47 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | PF-06650808, PF06650808, PF06650808 |
| 背景 | Neurogenic locus notch homolog protein 3 (NOTCH3) is a ~243 kDa protein. Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD), it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. 1. Peters, N. et al. (2004) Experimental cell research 299, 454-64. PMID: 15350543 2. Joutel, A. et al. (2004) American journal of human genetics 74, 338-47. PMID: 14714274 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human NOTCH3 (PF-06650808)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
