Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO) (HB745016)

Name: Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO)
Brand: abinScience
SKU: HB745016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB745016
Description	Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO) (HB745016) is a human monoclonal antibody detecting OSM/Oncostatin-M. Expressed in Mammalian cells.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG
ID de clone	GSK 2330811
Système d'expression	Mammalian cells
Cible	Oncostatin-M, OSM
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P13725
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	GSK-2330811, GSK2330811, GSK2330811
Contexte	Oncostatin-M (OSM) is a ~28 kDa protein. Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
Reférences	1. Denton CP, et al. Biological and clinical insights from a randomized phase 2 study of an anti-oncostatin M monoclonal antibody in systemic sclerosis. Rheumatology (Oxford). 2022 Dec 23;62(1):234-242. [HB745016]
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human OSM/Oncostatin-M (GSK 2330811)

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Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO).pdf

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