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| カタログ番号 | HB745016 |
|---|---|
| 説明 |
Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO) (HB745016) is a human monoclonal antibody detecting OSM/Oncostatin-M. Expressed in Mammalian cells.
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | GSK 2330811 |
| 発現システム | Mammalian cells |
| ターゲット | Oncostatin-M, OSM |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P13725 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | GSK-2330811, GSK2330811, GSK2330811 |
| 背景 | Oncostatin-M (OSM) is a ~28 kDa protein. Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). |
| 参考文献 | 1. Denton CP, et al. Biological and clinical insights from a randomized phase 2 study of an anti-oncostatin M monoclonal antibody in systemic sclerosis. Rheumatology (Oxford). 2022 Dec 23;62(1):234-242. [HB745016] |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human OSM/Oncostatin-M (GSK 2330811)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
