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Anti-Human PDGF-B Reference Antibody (MOR-8457, RUO) (HF877016)

Anti-Human PDGF-B Reference Antibody (MOR-8457, RUO)
Anti-Human PDGF-B Reference Antibody (MOR-8457, RUO)
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Aperçu
Numéro de catalogueHF877016
Description
Anti-Human PDGFB (MOR-8457) (HF877016) is a research-grade recombinant antibody targeting PDGF-2. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG
ID de cloneMOR-8457
Système d'expression Mammalian cells
Cible PDGF-2, Proto-oncogene c-Sis, PDGF2, SIS, Platelet-derived growth factor B chain, PDGFB, Becaplermin, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, PDGF subunit B
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P01127
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsMOR-8457, MOR8457, MOR8457
Contexte

Platelet-derived growth factor subunit B (PDGFB) is a ~27 kDa protein. Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing.

1. Vanlandewijck, M. et al. (2015) PloS one 10, e0143407. PMID: 26599395
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human PDGF-B Reference Antibody (MOR-8457, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human PDGFB (MOR-8457)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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