Anti-Human PDGF-B Reference Antibody (MOR-8457, RUO) (HF877016)

Name: Anti-Human PDGF-B Reference Antibody (MOR-8457, RUO)
Brand: abinScience
SKU: HF877016
Price: 370 USD
Availability: InStock

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Обзор

Каталожный номер	HF877016
Описание	Anti-Human PDGFB (MOR-8457) (HF877016) is a research-grade recombinant antibody targeting PDGF-2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG
ID клона	MOR-8457
Система экспрессии	Mammalian cells
Цель	PDGF-2, Proto-oncogene c-Sis, PDGF2, SIS, Platelet-derived growth factor B chain, PDGFB, Becaplermin, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, PDGF subunit B
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P01127
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	MOR-8457, MOR8457, MOR8457
Фон	Platelet-derived growth factor subunit B (PDGFB) is a ~27 kDa protein. Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. 1. Vanlandewijck, M. et al. (2015) PloS one 10, e0143407. PMID: 26599395
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human PDGFB (MOR-8457)

Ссылки

Даташит

Anti-Human PDGF-B Reference Antibody (MOR-8457, RUO).pdf

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Formula

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