Anti-Human PLA2G1B Reference Antibody (DIACC 1010, RUO) (HY504016)

Name: Anti-Human PLA2G1B Reference Antibody (DIACC 1010, RUO)
Brand: abinScience
SKU: HY504016
Price: 326 USD
Availability: InStock

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Vista general

Número de catálogo	HY504016
Descripción	Anti-Human PLA2G1B/PLA2 (DIACC 1010) (HY504016) is a research-grade recombinant antibody targeting Phospholipase A2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	DIACC 1010
Sistema de expresión	Mammalian cells
Objetivo	Phospholipase A2, PLA2G1B, Group IB phospholipase A2, PLA2A, PPLA2, Phosphatidylcholine 2-acylhydrolase 1B, PLA2
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P04054
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	DIACC-1010, DIACC1010, DIACC1010
Fondo	Phospholipase A2 (PLA2G1B/PLA2) is a ~16 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets dietary phospholipids in the intestinal tract. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines. May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation in the intestinal tract. Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines. May act in an autocrine and paracrine manner. 1. Suzuki, N. et al. (2000) The Journal of biological chemistry 275, 5785-93. PMID: 10681567 2. Kanda, A. et al. (1992) Biochimica et biophysica acta 1171, 1-10. PMID: 1420353 3. Yu, BZ. et al. (2007) Biochimica et biophysica acta 1768, 2478-90. PMID: 17603006 4. Pan, Y. et al. (2014) Scientific reports 4, 6660. PMID: 25335547 5. Ancian, P. et al. (1995) The Journal of biological chemistry 270, 8963-70. PMID: 7721806
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human PLA2G1B/PLA2 (DIACC 1010)

Referencias

Datasheet

Anti-Human PLA2G1B Reference Antibody (DIACC 1010, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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