Anti-Human PLA2G1B Reference Antibody (DIACC 1010, RUO) (HY504016)

Name: Anti-Human PLA2G1B Reference Antibody (DIACC 1010, RUO)
Brand: abinScience
SKU: HY504016
Price: 326 USD
Availability: InStock

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Обзор

Каталожный номер	HY504016
Описание	Anti-Human PLA2G1B/PLA2 (DIACC 1010) (HY504016) is a research-grade recombinant antibody targeting Phospholipase A2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG
ID клона	DIACC 1010
Система экспрессии	Mammalian cells
Цель	Phospholipase A2, PLA2G1B, Group IB phospholipase A2, PLA2A, PPLA2, Phosphatidylcholine 2-acylhydrolase 1B, PLA2
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P04054
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	DIACC-1010, DIACC1010, DIACC1010
Фон	Phospholipase A2 (PLA2G1B/PLA2) is a ~16 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets dietary phospholipids in the intestinal tract. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines. May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation in the intestinal tract. Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines. May act in an autocrine and paracrine manner. 1. Suzuki, N. et al. (2000) The Journal of biological chemistry 275, 5785-93. PMID: 10681567 2. Kanda, A. et al. (1992) Biochimica et biophysica acta 1171, 1-10. PMID: 1420353 3. Yu, BZ. et al. (2007) Biochimica et biophysica acta 1768, 2478-90. PMID: 17603006 4. Pan, Y. et al. (2014) Scientific reports 4, 6660. PMID: 25335547 5. Ancian, P. et al. (1995) The Journal of biological chemistry 270, 8963-70. PMID: 7721806
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human PLA2G1B/PLA2 (DIACC 1010)

Ссылки

Даташит

Anti-Human PLA2G1B Reference Antibody (DIACC 1010, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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