Anti-Human PTH Reference Antibody (ABX-PTH, RUO) (HF921016)

Name: Anti-Human PTH Reference Antibody (ABX-PTH, RUO)
Brand: abinScience
SKU: HF921016
Price: 326 USD
Availability: InStock

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Número de catálogo	HF921016
Descripción	Anti-Human PTH (ABX-PTH) (HF921016) is a research-grade recombinant antibody targeting Parathyroid hormone. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	ABX-PTH
Sistema de expresión	Mammalian cells
Objetivo	Parathyroid hormone, Parathormone, PTH, Parathyrin
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P01270
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	ABX-PTH, ABXPTH, ABXPTH
Fondo	Parathyroid hormone (PTH) is a ~12 kDa protein. Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. 1. Shimizu, N. et al. (2001) The Journal of biological chemistry 276, 49003-12. PMID: 11604398 2. Kobayashi, K. et al. (2022) Molecular cell 82, 3468-3483.e5. PMID: 35932760 3. Pioszak, AA. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 5034-9. PMID: 18375760 4. Zoidis, E. et al. (2011) Molecular and cellular biochemistry 348, 33-42. PMID: 21076856
Nota	For research use only. Not suitable for clinical or therapeutic use.