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Anti-Human PTH Reference Antibody (ABX-PTH, RUO) (HF921016)

Anti-Human PTH Reference Antibody (ABX-PTH, RUO)
Anti-Human PTH Reference Antibody (ABX-PTH, RUO)
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Aperçu
Numéro de catalogueHF921016
Description
Anti-Human PTH (ABX-PTH) (HF921016) is a research-grade recombinant antibody targeting Parathyroid hormone. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG
ID de cloneABX-PTH
Système d'expression Mammalian cells
Cible Parathyroid hormone, Parathormone, PTH, Parathyrin
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P01270
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsABX-PTH, ABXPTH, ABXPTH
Contexte

Parathyroid hormone (PTH) is a ~12 kDa protein. Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.

1. Shimizu, N. et al. (2001) The Journal of biological chemistry 276, 49003-12. PMID: 11604398
2. Kobayashi, K. et al. (2022) Molecular cell 82, 3468-3483.e5. PMID: 35932760
3. Pioszak, AA. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 5034-9. PMID: 18375760
4. Zoidis, E. et al. (2011) Molecular and cellular biochemistry 348, 33-42. PMID: 21076856
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human PTH Reference Antibody (ABX-PTH, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human PTH (ABX-PTH)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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