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Anti-Human Glucose transporter GLUT-8 Reference Antibody (VB1-050, RUO) (HP075016)

Anti-Human Glucose transporter GLUT-8 Reference Antibody (VB1-050, RUO)
Anti-Human Glucose transporter GLUT-8 Reference Antibody (VB1-050, RUO)
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Aperçu
Numéro de catalogueHP075016
Description
Anti-Human SLC2A8/GLUT8 (VB1-050) (HP075016) is a research-grade recombinant antibody targeting Glucose transporter type X1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG
ID de cloneVB1-050
Système d'expression Mammalian cells
Nature Recombinant
Cible Glucose transporter type X1, GLUT-8, Glucose transporter type 8, GLUTX1, SLC2A8, Solute carrier family 2, facilitated glucose transporter member 8, GLUT8
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q9NY64
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsVB1-050, VB1050, VB1050
Contexte

Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8GLUT8) is a ~50 kDa protein. Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate.

1. Mayer, AL. et al. (2016) Scientific reports 6, 38586. PMID: 27922102
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human Glucose transporter GLUT-8 Reference Antibody (VB1-050, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human SLC2A8GLUT8 (VB1-050)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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