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Anti-Human TGF-beta 1 Reference Antibody (SAR-439459, RUO) (HF977076)

Anti-Human TGF-beta 1 Reference Antibody (SAR-439459, RUO)
Anti-Human TGF-beta 1 Reference Antibody (SAR-439459, RUO)
Anti-Human TGF-beta 1 Reference Antibody (SAR-439459, RUO)
Anti-Human TGF-beta 1 Reference Antibody (SAR-439459, RUO)
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  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
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Vista general
Número de catálogoHF977076
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG
ID de clonSAR-439459
Objetivo LAP, Latency-associated peptide, TGF-beta-1, TGFB, TGFB1, Transforming growth factor beta-1, Transforming growth factor beta-1 proprotein
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P01137
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosSAR-439459, SAR439459, SAR439459
Fondo

Transforming growth factor beta-1 proprotein (TGFB1) is a ~44 kDa protein. Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.

Referencias 1. Greco R, et al. Pan-TGFβ inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade. Oncoimmunology. 2020 Sep 13;9(1):1811605. [HF977076]
Nota For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Imágenes
  • Anti-Human TGF-beta 1 Reference Antibody (SAR-439459, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human TGFB1/TGF-beta-1 (SAR-439459)

  • Anti-Human TGF-beta 1 Reference Antibody (SAR-439459, RUO)

    Bioactivity

    Detects recombinant TGFB1 (Catalog No: HF977011) in indirect ELISA.

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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