



| Número de catálogo | HF977076 |
|---|---|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Especie huésped | Human |
| Clonalidad | Monoclonal |
| Isotipo | IgG |
| ID de clon | SAR-439459 |
| Objetivo | LAP, Latency-associated peptide, TGF-beta-1, TGFB, TGFB1, Transforming growth factor beta-1, Transforming growth factor beta-1 proprotein |
| Nivel de endotoxinas | < 10 EU/mg |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P01137 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | SAR-439459, SAR439459, SAR439459 |
| Fondo | Transforming growth factor beta-1 proprotein (TGFB1) is a ~44 kDa protein. Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. |
| Referencias | 1. Greco R, et al. Pan-TGFβ inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade. Oncoimmunology. 2020 Sep 13;9(1):1811605. [HF977076] |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) |

SDS-PAGE for Research Grade Anti-Human TGFB1/TGF-beta-1 (SAR-439459)

Detects recombinant TGFB1 (Catalog No: HF977011) in indirect ELISA.




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