Anti-Human Tenascin C Reference Antibody (ST2485, RUO) (HB274036)

Name: Anti-Human Tenascin C Reference Antibody (ST2485, RUO)
Brand: abinScience
SKU: HB274036
Price: 326 USD
Availability: InStock

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Numéro de catalogue	HB274036
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG
ID de clone	ST2485
Activité biologique	as well as in a xenograft model. ST2485 binds human tenascin at an epitope partially shared with BC2. ST2485 cross-reacts with murine tenascin. ST2485 can be studied in antitumor research [1].
Système d'expression	Mammalian cells
Cible	Myotendinous antigen, Neuronectin, GMEM, Tenascin, Tenascin-C, TN-C, TNC, TN, Cytotactin, GP 150-225, Glioma-associated-extracellular matrix antigen, HXB, Hexabrachion, JI
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P24821
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ST2485
Contexte	Tenascin (Tenascin-C/TNC) is a ~240 kDa protein. Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. 1. Martina, E. et al. (2010) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24, 778-87. PMID: 19884327
Reférences	1. Petronzelli, F., et al., (2005). Improved tumor targeting by combined use of two antitenascin antibodies. Clinical cancer research: an official journal of the American Association for Cancer Research, 11(19 Pt 2), 7137s–7145s. [HB274036]
Note	For research use only. Not suitable for clinical or therapeutic use.