Anti-Human Tenascin C Reference Antibody (ST2485, RUO) (HB274036)

Name: Anti-Human Tenascin C Reference Antibody (ST2485, RUO)
Brand: abinScience
SKU: HB274036
Price: 326 USD
Availability: InStock

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Каталожный номер	HB274036
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG
ID клона	ST2485
Биологическая активность	as well as in a xenograft model. ST2485 binds human tenascin at an epitope partially shared with BC2. ST2485 cross-reacts with murine tenascin. ST2485 can be studied in antitumor research [1].
Система экспрессии	Mammalian cells
Цель	Myotendinous antigen, Neuronectin, GMEM, Tenascin, Tenascin-C, TN-C, TNC, TN, Cytotactin, GP 150-225, Glioma-associated-extracellular matrix antigen, HXB, Hexabrachion, JI
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P24821
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	ST2485
Фон	Tenascin (Tenascin-C/TNC) is a ~240 kDa protein. Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. 1. Martina, E. et al. (2010) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24, 778-87. PMID: 19884327
Ссылки	1. Petronzelli, F., et al., (2005). Improved tumor targeting by combined use of two antitenascin antibodies. Clinical cancer research: an official journal of the American Association for Cancer Research, 11(19 Pt 2), 7137s–7145s. [HB274036]
Примечание	For research use only. Not suitable for clinical or therapeutic use.