Anti-Human TSLPR/CRLF2 Reference Antibody (RG-7258, RUO) (HP521026)

Name: Anti-Human TSLPR/CRLF2 Reference Antibody (RG-7258, RUO)
Brand: abinScience
SKU: HP521026
Price: 370 USD
Availability: InStock

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Número de catálogo	HP521026
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	RG-7258
Sistema de expresión	Mammalian cells
Objetivo	Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR, Thymic stromal lymphopoietin protein receptor, TSLP receptor, CRLF2, CRL2, ILXR, TSLPR
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q9HC73
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	RG-7258, RG7258, RG7258
Fondo	Cytokine receptor-like factor 2 (TSLPR/CRLF2) is a ~42 kDa protein. Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system.
Referencias	1. Fuentes M E, et al. Anti-TSLPR antibody RG7258 blocks dendritic cell activation, mast cell cytokine release and reduces Th2 inflammation in a non-human primate model of allergic lung inflammation[M]//B32. ALLERGIC INFLAMMATION: MECHANISMS. American Thoracic Society, 2011: A2767-A2767. [HP521026]
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107)